Do count-based differential expression methods perform poorly when genes are expressed in only one condition?

Xiaobei Zhou1,2 and Mark D. Robinson1,2,*

1 Institute of Molecular Life Sciences, University of Zurich, Winterthurerstrasse 190 CH-8057 Zurich, Switzerland
2 SIB Swiss Institute of Bioinformatics, University of Zurich, Zurich, Switzerland

* Corresponding author:


A Correspondence to Comprehensive evaluation of differential gene expression analysis methods for RNA-seq data by Rapaport F, Khanin R, Liang Y, Pirun M, Krek A, Zumbo P, Mason CE, Socci ND and Betel D
Genome Biol 2013, 14:R95